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Cannabis targets cancer without harming healthy cells

?What is special about cannabinoids in cancer treatment is their capacity to only induce programmed cell death (apoptosis) in cancer cells, but not in healthy cells?, explains Dr Franjo Grotenhermen, chairman of ?Medical Cannabis Declaration?. ?This makes cannabinoids unique and fundamentally different from standard chemotherapeutics which can cause severe side effects by harming healthy cells.?
All chemotherapeutics harm rapidly growing tissues, which causes the usual side effects like hair loss, nausea, impairment of blood formation and others. The cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) however, the most important compounds of the cannabis plant, spare healthy cells and target specifically cancer cells. Although signs of inhibition of cancer through cannabis were discovered in the nineties ? cannabis smokers had significantly less lung cancer as was expected from the harmful substances in the smoke ? the potential for cancer prevention was only discovered in recent years. It is now intensely researched worldwide.
The charity ?Medical cannabis Declaration (MCD)? aims to inform about the medical potential of cannabis in a global information campaign in ten languages and to improve access to cannabis as medicine for patients.
The campaign is financed by crowdfunding through the well-known platform Indiegogo: www.indiegogo.com/projects/say-yes-to-cannabis-as-medicine–5
The scientific journal ?Current Oncology? recently published a special issue on cannabis in cancer therapy, titled ?Use of Cannabinoids in Cancer Care?. So far the most extensive document on the topic, the article shows the many facets of THC and CBD in cancer treatment.
In April 2016 the working group of Burkhard Hinz at Rostock University presented in a review how cannabinoids target cancer cells (?Antitumorigenic targets of cannabinoids ? current status and implications?). The authors state in the outlook: ?Considering the remarkable safety profile of cannabinoid compounds, in particular that of CBD, introduction of cannabinoid compounds may serve as a considerable tool cancer patients would benefit from?.
Another scientific paper, also published this year, investigates how intensely the topic of cannabinoids and cancer is researched at the moment. In the article ?Anticancer mechanisms of cannabinoids?, Guillermo Velasco and his colleagues from the University of Madrid conclude: ?To summarize, cannabinoids induce tumour cell death and inhibit tumour angiogenesis and invasion in animal models of cancer, and there are indications that they act similarly in patients with glioblastoma. Given that cannabinoids show an acceptable safety profile, clinical trials testing them as single drugs or, ideally, in combination therapies in glioblastoma and other types of cancer are both warranted and urgently needed.?
Two different mechanisms seem to play a role in inhibiting tumor growth through cannabinoids, apoptosis and angiogenesis. Both effects are probably caused by cannabinoids binding with cannabinoid receptors. Other effects discussed by scientists are inhibition of cell division, reduced formation of metastases and less spreading to surrounding tissue, as well as interference with the waste regime of the cancer cells which can lead to their death.
This information was created as part of the ?Medical Cannabis Declaration (MCD)? charity?s ongoing global information campaign ?Say Yes to Cannabis as Medicine?. A list of the latest literature on cannabinoids and cancer is available at www.cannabis-med.org
Cannabis is successfully used for the treatment of cancer, multiple sclerosis, loss of appetite and nausea during chemo therapy, epilepsy, chronic pain diseases, severe depression, post-traumatic stress disorder or chronic inflammatory diseases.
On 19 April 2016, MCD kicked off a crowdfunding campaign at the platform Indiegogo to finance videos and online lectures in the ten most spoken languages of the world for its information campaign. After only two weeks the crowdfunding raised 6% of the target sum of 85,000 $. The campaign ?Say Yes to Cannabis as Medicine? will continue until mid-June:
Two videos on ?Cannabis as Medicine?: www.medical-cannabis-declaration.org/videos/
First lecture on ?Cannabis as Medicine? http://medical-cannabis-declaration.org/database/
One of the campaign?s goals is to give patients better access to cannabis as medicine. Only 10 out of 200 countries in the world grand their citizens access to cannabis for medical use. Another 20 countries established regulations that make cannabis as medicine accessible only in a few special cases, while in more than 150 countries legal access to this treatment remains unavailable.
MCD would like to thank the long-time supporter Dr Bronner (USA), along with crowdfunding silver level donors HempConsult (Germany) and MH medical hemp (Germany) for their contribution.
The campaign will post about its progress on Twitter using the Hashtag #YesToMedicalCannabis
About Medical Cannabis Declaration e.V. (MCD)
The Medical Cannabis Declaration (MCD) is an online platform founded on 16 February 2013 in Ruethen, Germany, established by worldwide medical professionals and patients who believe that the access to cannabis should not be determined by geography. MCD aims at promoting safe and regular prescription and use of medical cannabis, globally. The charity wants to be part of a growing movement to change the negative perception on cannabis to assure its real medical values are recognised. We solely rely on scientific studies developed for the medical use of the cannabis plant. Visit us at: www.medical-cannabis-declaration.org/…
You can download a map showing legal access to medical cannabis around the world as well as campaign logos in high resolution at www.medical-cannabis-declaration.org/supporting-materials-for-the-campaign-2/

Responsible under press legislation (V.i.S.d.P.):
Medical Cannabis Declaration e. V.
Am Mildenweg 6, 59602 Ruethen, Germany
Dr Franjo Grotenhermen

Posted by on 3. May 2016. Filed under Electronics & Semiconductors, Picture Gallery. You can follow any responses to this entry through the RSS 2.0. You can leave a response or trackback to this entry

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